6th Global Experts Meeting on Parkinsons and Movement Disorders
Paris, France
Subhas Bhuin
Bangur Institute of Neurosciences, India
Title: Profile and Severity Correlation of Ataxia Patients in a Tertiary Care Institute in Eastern India
Biography
Biography: Subhas Bhuin
Abstract
Introduction - Clinical profile and severity correlation of ataxia patients in our population is still varied . This study is taken up to explore this aspect.
Methods - A cross-sectional study was conducted at XXX. Clinical parameters with severity correlation( SARA scale ) in selected patients was determined.
Results: In 188 patients , 127 had cerebellar ataxia(SCA 2, 3, 1 ,6 ,12 , MSA C , Wilsons disease) , 42 had sensory ataxia mainly Sensory ataxic GBS, CIDP variant(CISP) , Sjogrens and 19 had Mixed cerebellar sensory ataxia (Multiple sclerosis , Vitamin E deficiency ). Cerebellar ataxias had higher disability at presentation ( mean SARA score- 21.87) than mixed ataxias ( SARA – 19.68). Increase in SARA score was seen more in mixed ataxias (3.64) than cerebellar ( 3.01) . Disability progression is more in MSA C and SCA 2 has lesser degree of progression ( despite highest SARA score- 28.5 at presentation).
Conclusion - MSA C, SCA , Multiple sclerosis are majority in respective ataxia groups.. Maximum disability and progression is seen in MSA and SCA (SARA scale) . Chances of early detection and knowledge about progression of ataxia spectrum in our population is attempted.
Limitations : Further follow up of the patients with ataxia required to get a clear insight
Further Scope : Early diagnosis and management strategies can be validated for better management and prevention of deterioration to make the otherwise debilitating ataxia disorders a preventable one.
Conflict of interest- Nil
Keywords: Ataxia, Cerebellar , SARA Scale